ACE2 and Alzheimer disease: Using fixed‐effects sample size weighted meta‐analysis, we found 19 genetic variants that were associated with both AD and circulating ACE2 at the genome‐wide significance p < 5.00E‐08 for the cross‐trait meta‐analysis and suggestive trait‐specific significance p < 0.05 for AD and circulating ACE2 with the same directions of effect sizes (Table 1); 4, 1, 1, and 13 genetic variants are located at chromosome 6p21.32, 8p21.2‐p21.1, 17p13.2, and 19q13.32, respectively.