,6,7,8 While inherited mutations of KCNQ1 are primarily associated with cardiovascular pathologies (e.g., long QT syndrome 1 (LQT1), familial atrial fibrillation)4,9 and hearing loss,10 there are several lines of evidence suggesting that KCNQ1 is also involved in the regulation of insulin secretion.11 This evidence concerns the gene KCNQ1 and familial atrial fibrillation.