STAT3 and glioblastoma: In addition, in epileptic GBM patients, gene sets involved in epithelial-to-mesenchymal transition (EMT) and CEBP-β signaling were found to be down-regulated, however, the expression of the key mesenchymal transcription factors NF-κB p65, STAT3, and CEBP-β was not altered [83] (Table 5).