ATG5 and glioblastoma: Also, under hypoxia, it was shown a negative correlation in GBM between miR-224-3p and HIF-1α, VEGF, or ATG5 (autophagy-related gene 5) [56], a key molecule of autophagy, while downregulation of miR-224-3p led to an increase cell mobility and chemoresistance [56] (Table 4).