FAP and cancer: FAP was upregulated in several cancer types such as Bladder urothelial carcinoma (BLCA), Breast invasive carcinoma (BRCA), and Colon adenocarcinoma (COAD), Lymphoid neoplasm diffuse large B-cell lymphoma (DLBC), Esophageal carcinoma (ESCA), HNSC, Kidney renal clear cell carcinoma (KIRC), Pancreatio adenocarcinoma (PAAD), and Stomach adenocarcinoma (STAD) compared to match normal tissues (Fig. 1a).