FAP was upregulated in several cancer types such as Bladder urothelial carcinoma (BLCA), Breast invasive carcinoma (BRCA), and Colon adenocarcinoma (COAD), Lymphoid neoplasm diffuse large B-cell lymphoma (DLBC), Esophageal carcinoma (ESCA), HNSC, Kidney renal clear cell carcinoma (KIRC), Pancreatio adenocarcinoma (PAAD), and Stomach adenocarcinoma (STAD) compared to match normal tissues (Fig. 1a). The gene discussed is FAP; the disease is diffuse large B-cell lymphoma.