AKT1 and neoplasm: According to Dai et al. (9) HN can promote apoptosis and inhibit invasion and migration of nasopharyngeal carcinoma cells (CNE-2Z) in vitro and prevent tumor growth in vivo by regulating PI3K/AKT (phosphatidylinositol-3 OH kinase/ serine/threonine protein kinase) mechanisms (11).