SHBG and type 2 diabetes mellitus: Importantly, the relationship of SHBG and free T with T2D has been sparsely studied in sub-Saharan Africa (SSA), with scanty cross-sectional data showing high levels of SHBG in men living with T2D in Nigeria [14] and South Africa [15] and low levels of free T in men living with T2D from Ghana [16], Nigeria [17], and South Africa [15, 18].