C3 and hepatocellular carcinoma: The mRNA expression of C3 (F = 6.02, p = 0.000524), CYBC1 (F = 2.66, p = 0.0478), DNASE1L3 (F = 6.63, p = 0.000229), IRAK1 (F = 4.67, p = 0.00327), SERPINE1 (F = 3.73, p = 3.73) and SERPINE1 (F = 3.73, p = 0.0116) was statistically significant among the groups with different hepatocellular carcinoma clinical staging as shown in Figure 4D.