KIM-1, also known as T cell immunoglobulin or mucin-containing molecule, is a cellular receptor involved in immune function regulation and response to viral infections (136); it is expressed in proximal tubular cells in response to damage and is involved in promoting renal fibrosis; additionally, it has been found to be a potential marker of glomerular function, because of its increased expression in diabetic glomerulopathy. The gene discussed is HAVCR1; the disease is renal fibrosis.