Citalopram exposure induced changes in ANKRD37 and GDF11, important for hippocampal volume (Xu et al., 2022; Moigneu et al., 2023), Interestingly, in mice, infusion of GDF11 enhanced hippocampal neurogenesis and attenuated depression-like symptoms (Moigneu et al., 2023). This evidence concerns the gene GDF11 and depressive disorder.