These peptides inhibit PCa cell invasion by disrupting the assembly of the AR/FlnA/integrin β1 complex and activating downstream Rac1, FAK, and MMP-2 signaling pathways (Di Donato et al., 2015; Di Donato et al., 2021a; Di Donato et al., 2021b). The gene discussed is AR; the disease is posterior cortical atrophy.