Multiple studies reported associations between single nucleotide polymorphisms (SNPs) in IL-1β [rs16944] (Yucesoy et al., 2006), IL-6 [rs1800795], and TNFα [rs1800629] (Babić Leko et al., 2020) genes and AD risk although findings have been mixed (Mun et al., 2016; Ramos Dos Santos et al., 2016). This evidence concerns the gene IL1B and Alzheimer disease.