TP53 and astrocytoma (excluding glioblastoma): IDH mutant tumors include oligodendrogliomas (expressing a 1p/19q codeletion), astrocytomas, IDH mutants, grade 2 and 3 (expressing P53 and ATRX mutations), and astrocytomas, IDH mutants, grade 4 (expressing the CDKN2A/B mutation).