SERPINE1 and triple-A syndrome: RCT: Randomized Clinical Trial; PAI-1: Plasminogen Activator Inhibitor-1; TAFI: Thrombin Activatable Fibrinolysis Inhibitor; PAP: Plasmin AntiPlasmin Complex, also Plasmin-Antiplasmin Complex; tPA: Tissue Plasminogen Activator; TM: Thrombomodulin; TXA: Tranexamic Acid; EACA: Epsilon-Amino-Caproic Acid; AAA: Aortic Abdominal Aneurysm; ICU: Intensive Care Unit; CABG: Coronary Artery Bypass Graft.