We identified a subset of OV (e.g. AOCS-158, AOCS-057), BC (TCGA-D8-A1JL, TCGA-A2-A0YM, TCGA-D8-A27F and TCGA-EW-A1PB) and UCEC (TCGA-DF-A2KS, TCGA-D1-A1NW) cases that displayed relatively low tumour tissue levels of BRCA1 methylation (Figure 6C) (<70% median methylation post-correction), suggesting potential subclonal or heterozygous methylation in these cases. Here, BRCA1 is linked to neoplasm.