TNF and inflammatory bowel disease: In addition, Shu et al have highlighted that hepcidin concentrations are elevated in individuals with active disease versus IBD in remission and that hepcidin values correlate with IBD activity and severity of anemia, as well as with erythrocyte sedimentation rate (ESR), CRP, TNF‐alpha, IL‐6, and IL‐17 values (Shu et al., 2019).