Therefore, since ICAM‐1 is related to the development of cardiovascular diseases, Apigenin, Naringenin, and Vicenin‐2 can be considered cardioprotective in heart diseases involving diabetic animals (Ku & Bae, 2016; Liu et al., 2017; Mahajan et al., 2017; Ren et al., 2016). Here, ICAM1 is linked to cardiovascular disorder.