AKT1 and cancer: The mechanism of action of 6‐shogaol as an anticancer drug includes induction of paraptosis (a nonapoptotic path effective in cancer cell death) in breast cancer cells (Nedungadi et al., 2018), induction of apoptosis in liver cancer cells via the inactivation of Wnt (Zhang et al., 2021), the increase in the production of reactive oxygen species (ROS) in human colorectal carcinoma cells (Pan et al., 2008), induction of autophagy in MCF‐7 cancer stem cells, and the modulation of notch or the inhibition of AKT/mTOR signaling in lung cancer A549 cells (Hung et al., 2009; Ray et al., 2015).