Moreover, researchers suggest that obesity, characterized by elevated levels of leptin and decreased levels of adiponectin, may disrupt blood pressure regulation (71, 72).This imbalance in blood pressure regulation, in turn, weakens the arterial wall and increases arterial pressure, ultimately leading to arterial deformation and changes in hemodynamics, which can contribute to the progression of AAA (73–75). Here, ADIPOQ is linked to triple-A syndrome.