Changing the degree of m6A modification may alter the cell cycle of BC cells and stimulate the proliferation, metastasis and invasion of BC cells by affecting the activity of downstream targets and various signaling pathways, such as the B-cell lymphoma-2 (Bcl-2) and phosphatidylinositol 3-kinase/Protein Kinase B (PI3K/Akt) pathways (60). The gene discussed is AKT1; the disease is breast cancer.