DEA linked the downregulated genes to biological processes of activation of AP‐2 family of transcription factors (Tfab2a, Tfab2b2, Tfab2c), fatty acid biosynthesis (e.g., Lipc, Lipg), regulation of somatic (adult) stem cell population maintenance (e.g., Pax8, Hnf1b, Trp63, Hnf4a, Pklr) and maturity onset of diabetes of the young (Hnf4a, Pklr, Hnf1b). This evidence concerns the gene HNF1B and diabetes mellitus.