PRKAB1 and steatosis: HE staining results showed that: In Con, liver lobules were intact, hepatocytes were normal polygonal, nuclei were located in the center, uniform size, homogeneous staining of cytoplasm, and there was no significant steatosis; in Mod group, liver lobules were structurally abnormal, hepatocytes were enlarged and ballooned, and the whole liver tissue was diffusely steatotic; compared with the Mod group, the steatotic degeneration of hepatocytes in mice in the Acu + AMPK group and the Acu + ACC group was reduced to varying degrees.