Other relevant studies also suggested that plasma exosomes microRNAs (miR-409, miR-191, miR-21, miR-451a, miR-19b, miR-335-5p, miR-340-5p, miR-451,miR-720), mRNAs (CK18, CD63, FGA, KRT19, HIST1H2BK, ITIH2, MARCH2, CLDN1, MAL2, TIMP1, WASF2, and ARF6), small nucleolar RNAs (SNORA74A and SNORA25), and proteins (ZIP4, EphA2, ALIX, ADAM8) could assist to pancreatic cancer diagnosis [120–135]. Here, ITIH2 is linked to familial pancreatic carcinoma.