Other relevant studies also suggested that plasma exosomes microRNAs (miR-409, miR-191, miR-21, miR-451a, miR-19b, miR-335-5p, miR-340-5p, miR-451,miR-720), mRNAs (CK18, CD63, FGA, KRT19, HIST1H2BK, ITIH2, MARCH2, CLDN1, MAL2, TIMP1, WASF2, and ARF6), small nucleolar RNAs (SNORA74A and SNORA25), and proteins (ZIP4, EphA2, ALIX, ADAM8) could assist to pancreatic cancer diagnosis [120–135]. Here, CLDN1 is linked to familial pancreatic carcinoma.