These 31 genes were involved in epigenetic regulation (KMT2C, SETD2, EP300, KMT2D, TET2, DNMT3A, KMT2A, etc.), tumor suppression (FAT1, BCOR, BCORL1, ETV6, ARID1A, ATM, ARID2) and signaling pathways (NOTCH1, NOTCH2, TNFAIP3, NF1, TNFRSF14, MYD88, KLHL6, PDGFRB, SPEN, TET2, FAS, JAK3, NFKBIE, MTOR, RELN, CIITA, APC). The gene discussed is KMT2A; the disease is neoplasm.