Moreover, genetic rearrangements were detected in IgH, Igκ, or IgL clonal rearrangements (polypropylene gel electrophoresis in 19 cases), Fig. 1A, capillary electrophoresis in 12 cases, Fig. 1B), with IgHA and IgκA loci being the most common (Fig. 2); immunophenotypes: tumor cells showed positive results for CD20, CD79a, BCL-2 were mostly positive, CD3, CD5, CD10, CD23, Cyclin D1, and BCL-6 were mostly negative; CD43 showed the possibility of either being positive or negative, and tumor tissue Kappa or Lambda showed the possibility of restrictive expression (Fig. 3). The gene discussed is SPN; the disease is neoplasm.