Next, we focused on SNHG7 since it is highly expressed in the epidermis (Fig. 2B,C; Appendix Fig. S2), its expression is significantly changed in both AD and psoriasis (Fig. 1A,B), it strongly regulates clonogenicity (Fig. 2E), and its gene structure is relatively simple: SNHG7 encodes only two alternative lncRNAs (Dunham et al, 2012; Boone et al, 2020), each about 1 kb long, and contains two H/ACA box snoRNA genes, SNORA17A and SNORA17B, within its introns (Fig. 3A). Here, SNHG7 is linked to Alzheimer disease.