LINC-PINT and glioblastoma: In colon cancer, it works as a long non-coding RNA: it binds to the Polycomb Repressive Complex 2 and in so doing it prevents the transcription of pro-proliferation and pro-survival genes.208 Conversely, in glioblastoma, although it does not show coding capabilities per se, LINC-PINT undergoes back-splicing of exon 2.