RASSF1 and small cell lung carcinoma: However, the diagnostic sensitivity, specificity, DOR, and AUC for SCLC were 0.90 (0.84–0.94), 0.95 (0.94–0.97), 249.5 (103.94–598.8), and 0.98, respectively, showing that RASSF1A methylation may be a promising biomarker for SCLC diagnosis (sensitivity = 0.90>0.5, specificity = 0.95>0.90, DOR = 249.5, and AUC = 0.98>0.90) with both extremely high diagnostic and exclusion diagnostic value.