Similarly, treatment decreased basal ESC growth marked by Krt5, Aqp3, and Trp63 mRNA, alarmin signal marked by Il33 mRNA, immune activation marked by Serpinb2, Ltf, Cxcl17, and Nos2 mRNA, type 2 inflammation marked by Il13, Arg1, Trem2, and Il6 mRNA, and mucinous differentiation marked by Muc5ac, Clca1, and Muc5b mRNA (Figure 6, A–F), and attenuated mucinous differentiation tracked with Muc5ac and Muc5b immunostaining (Figure 6G) at 49 days after infection. The gene discussed is TREM2; the disease is infection.