Through the GSE121733 dataset from the Gene Expression Omnibus (GEO) database (https://www.ncbi.nlm.nih.gov/geo/), it has been observed that ID1 expression is significantly downregulated in KIS siRNA-transfected liver cancer cells, indicating ID1 as a potential downstream effector molecule of KIS in liver cancer; however, whether ID1 is regulated by KIS in LUAD remains to be determined. Here, ID1 is linked to liver cancer.