In immune cell recruitment to tumor (step 4), risk score was associated with T cell recruiting, CD4 T cell recruiting, CD8 T cell recruiting, Th1 cell recruiting, Th1 cell recruiting, Monocyte recruiting NK cell recruiting, Th17 cell recruiting, B cell recruiting and Treg cell recruiting were significantly negatively correlated, and Neutrophil recruiting, Eosinophil recruiting, Basophil recruiting and MDSC recruiting were significantly positively correlated (P < 0.05) (Fig. 7B). Here, CD4 is linked to neoplasm.