IKZF3 and neoplasm: In the multivariate analysis, IKZF3 amplification (P = 0.007, HR: 3.381 for DFS; P = 0.004, HR: 3.734 for OS) and tumor deposits (P < 0.001, HR: 1.334 for DFS; P = 0.003, HR: 2.519 for OS) were associated with DFS and OS (Table 2).