ERBB2 and gastric cancer: Several amplified genes including ERBB2 (Kanayama et al. 2018; Nakata et al. 2019; Ughetto et al. 2021), FGFR2 (Kunii et al. 2008), MET (Hou et al. 2019), TNK2 (Shinmura et al. 2014) have been identified significantly associated with advanced tumor grade and heightened aggressiveness in gastric cancer.