As shown in Figure 2A, CTHRC1 expression and the BRAF(V600E) mutation were positively correlated in these three types of tumors, with correlation coefficients of 0.139 in colon cancer (COAD, P < 0.05), 0.794 in thyroid cancer (THCA, P < 0.05), and 0.179 in melanoma (SKCM, P < 0.05), respectively. This evidence concerns the gene BRAF and malignant colon neoplasm.