In thyroid cancer patients, significant correlations were found between OS rates and risk factors, including tumor size (HR ═ 3.07) (P ═ 0.038), clinical stage (HR ═ 7.1) (P < 0.001), and CTHRC1 expression level (low and high) (HR ═ 3.03) (P ═ 0.027) (Table 2). The gene discussed is CTHRC1; the disease is thyroid cancer.