In thyroid cancer patients, CTHRC1 expression was positively correlated with tumor size (P ═ 0.018) and lymph node metastasis (P ═ 0.045), but there was no significant correlation between CTHRC1 expression and patients’ age, gender, distant metastasis, or clinical stage (P > 0.05) (Table 7). This evidence concerns the gene CTHRC1 and neoplasm.