In colon cancer, many types of immune cell infiltration (especially macrophages, neutrophils, dendritic cells, CD4+ T cells, and CD8+ T cells) were positively correlated with CTHRC1 expression, while a few types of immune cells, including Th17 cells and NK CD56 bright cells, were negatively correlated with CTHRC1 expression (Figure 5A and 5B). This evidence concerns the gene CTHRC1 and colonic neoplasm.