CD81 and breast neoplasm: Additionally, immunofluorescence analysis of breast tumours showed that BHS synergized with paclitaxel to significantly decrease the expression levels of CD81, CXCL1, and CD204, suggesting that BHS suppressed paclitaxel‐induced EV‐Apo biogenesis, CXCL1 secretion, and TAM infiltration (Figure 9h–i).