TRPS1 and mesenchymal cell neoplasm: It is worth noting that while our study may represent the first extensive immunohistochemical analysis of TRPS1 specifically targeting mesenchymal tumors or tumors of uncertain differentiation in the skin, initial documentation of TRPS1 immunohistochemical expression in non-epithelial and non-melanocytic skin cells occurred in reactive fibroblasts/myofibroblasts within dermal granulation tissues and scars [9].