These differences corresponded with decreasedcell proliferation and increased ROS production and apoptosis, asdetected in representative HCC tumor sections by Ki67, DCFH-DA, andTUNEL staining (Figures 6G and S27), with similar changes observedin the ANs- and AMPNs1-treated groups and marked changes observedin the AMPNs-treated group. The gene discussed is MKI67; the disease is hepatocellular carcinoma.