We thereforeanalyzed the effect of AMPNs treatment on tumor development in miceinjected with a high dose of Hepa1-6 cells in the right dorsal regionto produce similar size tumors, then treated with PBS, anti-PD-L1antibodies, AMPNs, or both AMPNs and anti-PD-L1 antibodies, and finallyreinjected with a high dose of Hepa1-6 cells in the left dorsal regionto mimic tumor recurrence after treatment (Figure S35A). The gene discussed is CD274; the disease is neoplasm.