HepYF-M13 and HepYF-M14 cells expressed HCC markers such as Hnf4a, Glul, Ggt1, Spp1, Golm1 and Tspan8, and did not express the well-differentiated HCC markers Arg1 and Alb (Fig. 1E). Here, HNF4A is linked to hepatocellular carcinoma.