UMOD and hypertensive disorder: In a study of serum uromodulin and its genetic variants about blood pressure and hypertension in Chinese adults, Chinese researchers found that rs12917707 and rs12708631 in the uromodulin gene were significantly associated with longitudinal blood pressure change over 8 years of follow-up and that rs12708631 was significantly associated with the 8-year incidence of hypertension (94).