uUMOD has often been used in various cohort studies of uromodulin and hypertension in populations, however, this does not mean that sUMOD is not associated with hypertension, as sUMOD was found to be significantly associated with a reduced risk of hypertension in a cohort study of adolescents with hypertension in Hanzhong City, China (94). The gene discussed is UMOD; the disease is hypertensive disorder.