In the literature, deletion or loss of heterozygosity (LOH) of the 1p36 chromosomal band is correlated with high-risk neuroblastoma features, including older age at diagnosis, metastatic disease, MYCN amplification and poor prognosis Unfavorable abnormalities also include segmental copy number alterations, such as loss of 3p, deletion or LOH 11q23, 14q23qter and gain of 17q (Marrano et al., 2017). This evidence concerns the gene MYCN and metastatic neoplasm.