KMT2A and acute myeloid leukemia: It is known that 4 °C cold exposure augments TATA in experimental mice by activation of the β3‐adrenoceptor sympathetic system.[17] To further study the role of β3‐adrenoceptor activation in leukemic suppression, a specific β3‐adrenoceptor agonist, CL‐316243,[18] was used to treat MLL‐NRIP3‐AML mice.