Similarly, ectopic expression of an MLL‐ALL1‐fused gene from chromosome 9 (AF9; also known as MLLT3 super elongation complex subunit) fusion protein was used as the second murine AML model.[15] Additionally, the intracellular Notch1 domain (ICN1)‐driven ALL model was also deployed in our study.[16] (Figure 1A). Here, KMT2A is linked to acute myeloid leukemia.