A previous study showed that high levels of HGF induced the homing of bone marrow mesenchymal stem cells (BMSCs)to the injured tissue by increasing the expression of miRNA‐221 and −26b through the activation of the AKT and focal adhesion kinase pathways.[24] One study showed that priming BMSCs with HGF enhanced vascular regeneration and restored cardiac function during myocardial infarction.[25]. This evidence concerns the gene AKT1 and myocardial infarction.