Finally, we selected six DEPs that were closely associated with sepsis: cathepsin B (CatB), vascular endothelial cell adhesion molecule (VCAM-1), neutrophil gelatinase-associated lipoprotein (NGAL), protein S100-A9, prosaposin, and thrombospondin-1 (TSP-1). Here, CTSB is linked to Sepsis.