FBW7 acts as a tumor suppressor by promoting the degradation of cancer-related proteins like Snail [126], Brahma-related gene 1 (Brg1) [127], and YTH N6-methyladenosine RNA Binding Protein F2 (YTHDF2) [128], thereby inhibiting metastasis in various cancers including non-small cell lung cancer, gastric cancer, and ovarian cancer. The gene discussed is SNAI1; the disease is cancer.