TMEFF1 and infection: Furthermore, bulk RNA-seq on cortical neurons derived from hPSCs from the two patients, TMEFF1-KO and parental WT hPSCs showed that TMEFF1 deficiency did not alter transcriptomic responses to IFNβ after 8 h of stimulation, or those to HSV-1 after 24 h of infection (Extended Data Fig. 4k,l).