In the same assays, infection by group B2 strain 71V, which only uses PCDH10 as a receptor, was unaffected, and an Fc fusion protein comprising the ectodomain of human MXRA8 (MXRA8ect–Fc), used as a negative control, had no effect on viral entry (Extended Data Figs. 4f and 8b). The gene discussed is PCDH10; the disease is infection.