The normal data set included 2833 normal samples and 4121 tumor samples from the GTEx dataset and tumor-adjacent normal tissue from the TCGA dataset (Table 4).COL12A1 expression was significantly increased in patients with breast (p < 0.0001), colorectal (p = <0.0001), head and heck (p = <0.0001), lung (p = <0.0001), pancreas (p = <0.0001), prostate (p = <0.0001) and gastric (p = <0.0001) cancer (Figure 4). This evidence concerns the gene COL12A1 and cancer.