GEPIA2 analysis indicated that high BUB1 expression was associated with OS in ACC, KIRC, KIRP, LGG, LIHC, LUAD, LUSC, and PAAD (P < 0.05) (Fig. S1A) and associated with DFS in ACC, KIRC, KIRP, LGG, LIHC, MESO, PAAD PRAD, SARC and THCA (P < 0.05) (Fig. S1B). Here, BUB1 is linked to pancreatic adenocarcinoma.