We found the ratios of sn-1 C16:0-containing PE/LPE 16:0/0:0 (Fig. 5p), and sn-1 C18:0-containing PE/LPE 18:0/0:0 (Fig. 5q) were significantly higher in 3-month AD compared to 3-month WT in the hippocampus. This evidence concerns the gene SLC38A3 and Alzheimer disease.