EGFR and malignant peripheral nerve sheath tumor: Erlotinib is an EGFR tyrosine kinase inhibitor, and although it has achieved some efficacy in the treatment of MPNST, the effect of combination therapy with other antitumour therapies remains unclear.Yonatan Y Mahller et al. investigated the efficacy of oHSV in combination with erlotinib in the treatment of MPNST [27].