Next, using multitrait GWAS analysis (MTAG, see Methods) on ACD and the prioritized traits (CAD, stroke, WMH), we identified intronic SNPs in SMG6 and ABCG8 to be GW significant (pMTAG < 1.67E‐08, for three phenotypes) for ACD (Table S10). This evidence concerns the gene SMG6 and Stroke.