Analysis of the keloid fibroblast transcriptome and protein levels upon IGFBP7 treatment revealed decreased levels of TGF-β1, Col I, VEGF, and pro-inflammatory markers interleukin-6 (IL-6) and interleukin-8 (IL-8), while levels of TGF-β3 were increased. Here, CXCL8 is linked to keloid.