FHIT and mastitis: Zhong et al. revealed that the promoter methylation levels of the FHIT and PIAS1 genes in the mastitis group were higher and lower, respectively, than those in the healthy group (Zhong et al., 2023) and Ju et al. reported that 8 of 13 InDel loci were polymorphic in the FHIT gene, with all the new InDel variants significantly related to six different milk traits (p < 0.05) (Ju et al., 2021).